Amla (Emblica officinalis Gaertn.) prevents dyslipidaemia and oxidative stress in the ageing process

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Amla (Emblica officinalis Gaertn.) prevents dyslipidaemia and oxidative stress in the ageing process.

Amla (Emblica officinalis Gaertn.) is widely used in Indian medicine for the treatment of various diseases. We have investigated the effects of amla on the lipid metabolism and protein expression involved in oxidative stress during the ageing process. SunAmla or ethyl acetate extract of amla, a polyphenol-rich fraction, was administered at a dose of 40 or 10 mg/kg body weight per d for 100 d to...

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Influence of amla (Emblica officinalis Gaertn.) on hypercholesterolemia and lipid peroxidation in cholesterol-fed rats.

The effects of amla on low-density lipoprotein (LDL) oxidation and cholesterol levels were investigated in vitro and in vivo using Cu(2+)-induced LDL oxidation and cholesterol-fed rats. SunAmla and ethyl acetate (EtOAc) extract of amla significantly inhibited thiobarbituric acid (TBA)-reactive substance level in the Cu(2+)-induced LDL oxidation and the effects were stronger than those of probuc...

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Amelioration of alcohol-induced oxidative stress by Emblica officinalis (amla) in rats.

The present study was aimed at investigating the ameliorative effect of Emblica (Phyllanthus Emblica L) fruit extract (EFE) against alcohol-induced oxidative changes in plasma biochemical profile in rats. Alcohol administration (5 g/kg body wt/day) for 60 days resulted in significantly (P<0.05) higher levels of plasma nitrite/nitrate (NOx), total bilirubin, creatinine, and abnormalities in lipi...

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Reduction of hexachlorocyclohexane-induced oxidative stress and cytotoxicity in rat liver by Emblica officinalis gaertn.

The effect of prefeeding of dehydrated E. officinalis (amla) powder at 5 and 10% levels on hexachlorocyclohexane (HCH)-induced changes in multicomponent antioxidant system and lipid peroxides in rat liver was studied. HCH induced significant elevation in hepatic malondialdehyde, conjugated dienes and hydroperoxides. The prefeeding of amla at 10% level could decrease the formation of these lipid...

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Phytochemical and Toxicity Study of Emblica Officinalis (amla)

In the present study, phytochemistry and toxicities (acute and chronic) of Emblica officinalis fruit (Amla) have been determined. The hydroalcoholic extract (HAE) of amla was prepared and its extractability was found to be 46.9%. Different chemical tests showed the presence of various active principles or phytoconstituents, viz., alkaloids, glycosides, reducing sugars, tannins, resins, saponins...

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ژورنال

عنوان ژورنال: British Journal of Nutrition

سال: 2007

ISSN: 0007-1145,1475-2662

DOI: 10.1017/s0007114507691971